MicroRNA-184 modulates canonical Wnt signaling through the regulation of frizzled-7 expression in the retina with ischemia-induced neovascularization

Aberrant activation of Wnt signaling contributes to ischemia-induced retinal neovascularization in oxygen-induced retinopathy (OIR), although the underlying mechanism is so far unclear. Here, we show that microRNA-184 (miR-184) is significantly down-regulated in the retina of OIR mice, and miR-184 n...

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Published in:FEBS Lett
Main Authors: Takahashi, Yusuke, Chen, Qian, Rajala, Raju V. S., Ma, Jian-xing
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406844/
https://ncbi.nlm.nih.gov/pubmed/25796186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.febslet.2015.03.010
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