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Identification of HBV-MLL4 Integration and Its Molecular Basis in Chinese Hepatocellular Carcinoma

To gain molecular insights of HBV integration that may contribute to HCC tumorigenesis, we performed whole transcriptome sequencing and whole genome copy number profiling of hepatocellular carcinoma (HCC) samples from 50 Chinese patients. We identified a total of 33 HBV-human integration sites in 16...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Dong, Hua, Zhang, Lan, Qian, Ziliang, Zhu, Xuehua, Zhu, Guanshan, Chen, Yunqin, Xie, Xiaoying, Ye, Qinghai, Zang, Jie, Ren, Zhenggang, Ji, Qunsheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406717/
https://ncbi.nlm.nih.gov/pubmed/25901726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123175
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