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Single-electron transmetalation in organoboron cross-coupling by photoredox/nickel dual catalysis

The routine application of C(sp3)-hybridized nucleophiles in cross-coupling reactions remains an unsolved challenge in organic chemistry. The sluggish transmetalation rates observed for the preferred organoboron reagents in such transformations are a consequence of the two-electron mechanism underly...

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Bibliographic Details
Published in:Science
Main Authors: Tellis, John C., Primer, David N., Molander, Gary A.
Format: Artigo
Language:Inglês
Published: 2014
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406487/
https://ncbi.nlm.nih.gov/pubmed/24903560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1253647
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