Increase in Red Blood Cell-Nitric Oxide Synthase Dependent Nitric Oxide Production during Red Blood Cell Aging in Health and Disease: A Study on Age Dependent Changes of Rheologic and Enzymatic Properties in Red Blood Cells

AIM: To investigate RBC-NOS dependent NO signaling during in vivo RBC aging in health and disease. METHOD: RBC from fifteen healthy volunteers (HC) and four patients with type 2 diabetes mellitus (DM) were separated in seven subpopulations by Percoll density gradient centrifugation. RESULTS: The pro...

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Bibliografische gegevens
Gepubliceerd in:PLoS One
Hoofdauteurs: Bizjak, Daniel Alexander, Brinkmann, Christian, Bloch, Wilhelm, Grau, Marijke
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2015
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Research Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406474/
https://ncbi.nlm.nih.gov/pubmed/25902315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0125206
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