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Integrin β4 Signaling Promotes Mammary Tumor Cell Adhesion to Brain Microvascular Endothelium by Inducing ErbB2-mediated Secretion of VEGF

Prior studies have indicated that the β4 integrin promotes mammary tumor invasion and metastasis by combining with ErbB2 and amplifying its signaling capacity. However, the effector pathways and cellular functions by which the β4 integrin exerts these effects are incompletely understood. To examine...

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Detalhes bibliográficos
Publicado no:Ann Biomed Eng
Main Authors: Fan, Jie, Cai, Bin, Zeng, Min, Hao, Yanyan, Giancotti, Filippo G., Fu, Bingmei M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406420/
https://ncbi.nlm.nih.gov/pubmed/21556948
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10439-011-0321-6
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