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Hepatic fatty acid uptake is regulated by the sphingolipid acyl chain length

Ceramide synthase 2 (CerS2) null mice cannot synthesize very-long acyl chain (C22-C24) ceramides resulting in significant alterations in the acyl chain composition of sphingolipids. We now demonstrate that hepatic triacylglycerol (TG) levels are reduced in liver but not in adipose tissue or skeletal...

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Publicat a:Biochim Biophys Acta
Autors principals: Park, Woo-Jae, Park, Joo-Won, Merrill, Alfred H., Storch, Judith, Pewzner-Jung, Yael, Futerman, Anthony H.
Format: Artigo
Idioma:Inglês
Publicat: 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4406097/
https://ncbi.nlm.nih.gov/pubmed/25241943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbalip.2014.09.009
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