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A Novel Mgp-Cre Knock-In Mouse Reveals an Anticalcification/Antistiffness Candidate Gene in the Trabecular Meshwork and Peripapillary Scleral Region
PURPOSE. Soft tissue calcification is a pathological condition. Matrix Gla (MGP) is a potent mineralization inhibitor secreted by cartilage chondrocytes and arteries' vascular smooth muscle cells. Mgp knock-out mice die at 6 weeks due to massive arterial calcification. Arterial calcification re...
Shranjeno v:
| izdano v: | Invest Ophthalmol Vis Sci |
|---|---|
| Main Authors: | , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
The Association for Research in Vision and Ophthalmology
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4406033/ https://ncbi.nlm.nih.gov/pubmed/25711639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.15-16460 |
| Oznake: |
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