Regorafenib treatment for advanced, refractory gastrointestinal stromal tumor: a report of the UK managed access program

BACKGROUND: Tyrosine kinase inhibitors (TKI) have revolutionized the treatment of gastrointestinal stromal tumors (GIST) although most patients develop resistance to first and second-line therapies. Regorafenib, an oral multi-targeted TKI, has demonstrated benefit in previously treated GIST patients...

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Detalhes bibliográficos
Publicado no:Clin Sarcoma Res
Main Authors: Kollàr, Attila, Maruzzo, Marco, Messiou, Christina, Cartwright, Elisabeth, Miah, Aisha, Martin-Liberal, Juan, Thway, Khin, McGrath, Ellen, Dunlop, Alison, Khabra, Komel, Seddon, Beatrice, Dileo, Palma, Linch, Mark, Judson, Ian, Benson, Charlotte
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405914/
https://ncbi.nlm.nih.gov/pubmed/25905001
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/2045-3329-4-17
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