The calcium-sensing receptor suppresses epithelial-to-mesenchymal transition and stem cell- like phenotype in the colon

BACKGROUND: The calcium sensing receptor (CaSR), a calcium-binding G protein-coupled receptor is expressed also in tissues not directly involved in calcium homeostasis like the colon. We have previously reported that CaSR expression is down-regulated in colorectal cancer (CRC) and that loss of CaSR...

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Detalhes bibliográficos
Publicado no:Mol Cancer
Principais autores: Aggarwal, Abhishek, Prinz-Wohlgenannt, Maximilian, Gröschel, Charlotte, Tennakoon, Samawansha, Meshcheryakova, Anastasia, Chang, Wenhan, Brown, Edward M, Mechtcheriakova, Diana, Kállay, Enikö
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405849/
https://ncbi.nlm.nih.gov/pubmed/25879211
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-015-0330-4
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