The non-peptide thrombopoietin receptor agonist eltrombopag stimulates megakaryopoiesis in bone marrow cells from patients with relapsed multiple myeloma

BACKGROUND: Thrombocytopenia is a significant problem in patients with relapsed or refractory multiple myeloma, precipitating a need for supportive platelet transfusions and necessitating decreases in delivered doses of chemotherapy. Eltrombopag is a non-peptide, small molecule thrombopoietin (TPO)...

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Vydáno v:J Hematol Oncol
Hlavní autoři: Jeong, Jee-Yeong, Levine, Michelle S, Abayasekara, Nirmalee, Berliner, Nancy, Laubach, Jacob, Vanasse, Gary J
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2015
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405817/
https://ncbi.nlm.nih.gov/pubmed/25886818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-015-0136-2
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