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RasGAP Promotes Autophagy and Thereby Suppresses Platelet-Derived Growth Factor Receptor-Mediated Signaling Events, Cellular Responses, and Pathology

Platelet-derived growth factors (PDGFs) and their receptors (PDGFRs) make profound contributions to both physiology and pathology. While it is widely believed that direct (PDGF-mediated) activation is the primary mode of activating PDGFRs, the discovery that they can also be activated indirectly beg...

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Библиографические подробности
Опубликовано в: :Mol Cell Biol
Главные авторы: Lei, Hetian, Qian, Cynthia X., Lei, Jinghu, Haddock, Luis J., Mukai, Shizuo, Kazlauskas, Andrius
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2015
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405646/
https://ncbi.nlm.nih.gov/pubmed/25733681
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01248-14
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