Promyelocytic Leukemia Protein Isoform II Promotes Transcription Factor Recruitment To Activate Interferon Beta and Interferon-Responsive Gene Expression

To trigger type I interferon (IFN) responses, pattern recognition receptors activate signaling cascades that lead to transcription of IFN and IFN-stimulated genes (ISGs). The promyelocytic leukemia (PML) protein has been implicated in these responses, although its role has not been defined. Here, we...

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Veröffentlicht in:Mol Cell Biol
Hauptverfasser: Chen, Yixiang, Wright, Jordan, Meng, Xueqiong, Leppard, Keith N.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405644/
https://ncbi.nlm.nih.gov/pubmed/25733689
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01478-14
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