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Lipid-Overloaded Enlarged Adipocytes Provoke Insulin Resistance Independent of Inflammation

In obesity, adipocyte hypertrophy and proinflammatory responses are closely associated with the development of insulin resistance in adipose tissue. However, it is largely unknown whether adipocyte hypertrophy per se might be sufficient to provoke insulin resistance in obese adipose tissue. Here, we...

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Detalhes bibliográficos
Publicado no:Mol Cell Biol
Main Authors: Kim, Jong In, Huh, Jin Young, Sohn, Jee Hyung, Choe, Sung Sik, Lee, Yun Sok, Lim, Chun Yan, Jo, Ala, Park, Seung Bum, Han, Weiping, Kim, Jae Bum
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405637/
https://ncbi.nlm.nih.gov/pubmed/25733684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01321-14
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