Lipid-Overloaded Enlarged Adipocytes Provoke Insulin Resistance Independent of Inflammation

In obesity, adipocyte hypertrophy and proinflammatory responses are closely associated with the development of insulin resistance in adipose tissue. However, it is largely unknown whether adipocyte hypertrophy per se might be sufficient to provoke insulin resistance in obese adipose tissue. Here, we...

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Publicat a:Mol Cell Biol
Autors principals: Kim, Jong In, Huh, Jin Young, Sohn, Jee Hyung, Choe, Sung Sik, Lee, Yun Sok, Lim, Chun Yan, Jo, Ala, Park, Seung Bum, Han, Weiping, Kim, Jae Bum
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405637/
https://ncbi.nlm.nih.gov/pubmed/25733684
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01321-14
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