Pentadecapeptide BPC 157 Reduces Bleeding and Thrombocytopenia after Amputation in Rats Treated with Heparin, Warfarin, L-NAME and L-Arginine

BACKGROUND: BPC 157 is a stable gastric pentadecapeptide recently implicated with a role in hemostasis. While NO is largely implicated in hemostatic mechanisms, in tail-amputation-models under heparin- and warfarin-administration, both the NO-synthase (NOS)-blocker, L-NAME (prothrombotic) and the NO...

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Vydáno v:PLoS One
Hlavní autoři: Stupnisek, Mirjana, Kokot, Antonio, Drmic, Domagoj, Hrelec Patrlj, Masa, Zenko Sever, Anita, Kolenc, Danijela, Radic, Bozo, Suran, Jelena, Bojic, Davor, Vcev, Aleksandar, Seiwerth, Sven, Sikiric, Predrag
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2015
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405609/
https://ncbi.nlm.nih.gov/pubmed/25897838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0123454
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