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Overexpression of ERG and Wild-Type PTEN Are Associated with Favorable Clinical Prognosis and Low Biochemical Recurrence in Prostate Cancer

OBJECTIVES: The aim of this study was to investigate the expression of two commonly altered genes ERG and PTEN in prostate cancer (PC) and evaluate their prognostic significance. Despite conflicting published results, TMPRSS2-ERG gene fusion and PTEN loss are generally considered unfavorable markers...

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Pubblicato in:PLoS One
Autori principali: Kim, Sung Han, Kim, Soo Hee, Joung, Jae Young, Lee, Geon Kook, Hong, Eun Kyung, Kang, Kyung Min, Yu, Ami, Nam, Byung Ho, Chung, Jinsoo, Seo, Ho Kyung, Park, Weon Seo, Lee, Kang Hyun
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405492/
https://ncbi.nlm.nih.gov/pubmed/25897494
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0122498
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