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Shank1 regulates excitatory synaptic transmission in mouse hippocampal Parvalbumin-expressing inhibitory interneurons
The Shank genes (SHANK1, 2, 3) encode scaffold proteins highly enriched in postsynaptic densities where they regulate synaptic structure in spiny neurons. Mutations in human Shank genes are linked to autism spectrum disorder (ASD) and schizophrenia. Shank1 mutant mice exhibit intriguing cognitive ph...
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| 發表在: | Eur J Neurosci |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4405481/ https://ncbi.nlm.nih.gov/pubmed/25816842 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/ejn.12877 |
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