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Transforming growth factor-β-activated kinase 1 resistance limits glucocorticoid responsiveness to Toll-like receptor 4-mediated inflammation

Glucocorticoids (GC) are among the most effective anti-inflammatory drugs, but are often associated with serious adverse effects or inadequate therapeutic responses. Here, we use activation of different Toll-like receptors (TLRs) by their respective ligands to evaluate context-specific GC sensitivit...

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Detalhes bibliográficos
Publicado no:Immunology
Main Authors: Kong, Fansheng, Laryea, Gloria, Liu, Zhiwei, Bhattacharyya, Sandip
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405331/
https://ncbi.nlm.nih.gov/pubmed/25521315
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12434
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