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Genetic Targeting of a Small Fluorescent Zinc Indicator to Cell Surface for Monitoring Zinc Secretion

[Image: see text] Numerous mammalian cells contain Zn(2+) in their secretory granules. During secretion, Zn(2+) is coreleased with granular cargos into extracellular medium so Zn(2+) serves as a convenient surrogate marker for tracking the dynamics of secretion. Fluorescent Zn(2+) sensors that can b...

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Bibliographische Detailangaben
Veröffentlicht in:ACS Chem Biol
Hauptverfasser: Li, Daliang, Liu, Lin, Li, Wen-Hong
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405262/
https://ncbi.nlm.nih.gov/pubmed/25572404
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cb5007536
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