Expansion of CREB's DNA recognition specificity by Tax results from interaction with Ala-Ala-Arg at positions 282-284 near the conserved DNA-binding domain of CREB.

The transactivator protein of human T-lymphotropic virus type I (HTLV-I), Tax, forms multiprotein complexes with the ubiquitous transcription factor CREB and the CREB/ATF-1 heterodimer. The interaction between Tax and CREB is highly specific and results in increased binding of the Tax/CREB complexes...

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Vydáno v:	Proc Natl Acad Sci U S A
Hlavní autoři:	Adya, N, Zhao, L J, Huang, W, Boros, I, Giam, C Z
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	National Academy of Sciences 1994
Témata:	Research Article
On-line přístup:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC44052/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8202541/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.91.12.5642
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Expansion of CREB's DNA recognition specificity by Tax results from interaction with Ala-Ala-Arg at positions 282-284 near the conserved DNA-binding domain of CREB.

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