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Role of α-synuclein in inducing innate and adaptive immunity in Parkinson disease

Alpha-synuclein (α-syn) is central to the pathogenesis of Parkinson disease (PD). Gene duplications, triplications and point mutations in SNCA1, the gene encoding α-syn, cause autosomal dominant forms of PD. Aggregated and post-translationally modified forms of α-syn are present in Lewy bodies and L...

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Podrobná bibliografie
Vydáno v:J Parkinsons Dis
Hlavní autoři: Allen Reish, Heather E., Standaert, David G.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4405142/
https://ncbi.nlm.nih.gov/pubmed/25588354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JPD-140491
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