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Divergent and convergent evolution in metastases suggest treatment strategies based on specific metastatic sites

Background and objective: Systemic therapy for metastatic cancer is currently determined exclusively by the site of tumor origin. Yet, there is increasing evidence that the molecular characteristics of metastases significantly differ from the primary tumor. We define the evolutionary dynamics of met...

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Bibliografski detalji
Izdano u:Evol Med Public Health
Glavni autori: Cunningham, Jessica J., Brown, Joel S., Vincent, Thomas L., Gatenby, Robert A.
Format: Artigo
Jezik:Inglês
Izdano: Oxford University Press 2015
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404930/
https://ncbi.nlm.nih.gov/pubmed/25794501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emph/eov006
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