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Targeting leukemia by CD1c-restricted T cells specific for a novel lipid antigen

A subset of CD1c-restricted T lymphocytes exhibits strong reactivity against leukemia cells. These T cells recognize methyl-lysophosphatidic acid (mLPA), a novel lipid antigen produced by acute leukemia cells. Considering that CD1c-restricted T cells display efficacious anti-leukemia activities in a...

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Detalhes bibliográficos
Publicado no:Oncoimmunology
Main Authors: Lepore, Marco, de Lalla, Claudia, Mori, Lucia, Dellabona, Paolo, De Libero, Gennaro, Casorati, Giulia
Formato: Artigo
Idioma:Inglês
Publicado em: Taylor & Francis 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404883/
https://ncbi.nlm.nih.gov/pubmed/25949888
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/21624011.2014.970463
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