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The high mobility group A1 molecular switch: turning on cancer – can we turn it off?

INTRODUCTION: Emerging evidence demonstrates that the high mobility group A1 (HMGA1) chromatin remodeling protein is a key molecular switch required by cancer cells for tumor progression and a poorly differentiated, stem-like state. Because the HMGA1 gene and proteins are expressed at high levels in...

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Veröffentlicht in:Expert Opin Ther Targets
Hauptverfasser: Huso, Tait H, Resar, Linda MS
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404637/
https://ncbi.nlm.nih.gov/pubmed/24684280
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1517/14728222.2014.900045
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