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Th17, intestinal microbiota and the abnormal immune response in the pathogenesis of celiac disease

Celiac disease (CD) is an autoimmune enteropathy induced by the ingestion of gluten in genetically predisposed individuals who carry the HLA-DQ2 or -DQ8 alleles. The immune response is abnormal in celiac disease with small intestinal epithelial damage via CD8+CD4- intraepithelial lymphocytes. The et...

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Veröffentlicht in:Gastroenterol Hepatol Bed Bench
Hauptverfasser: Cicerone, Clelia, Nenna, Raffaella, Pontone, Stefano
Format: Artigo
Sprache:Inglês
Veröffentlicht: Shaheed Beheshti University of Medical Sciences 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404588/
https://ncbi.nlm.nih.gov/pubmed/25926936
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