Genome-wide next-generation DNA and RNA sequencing reveals a mutation that perturbs splicing of the phosphatidylinositol glycan anchor biosynthesis class H gene (PIGH) and causes arthrogryposis in Belgian Blue cattle

BACKGROUND: Cattle populations are characterized by regular outburst of genetic defects as a result of the extensive use of elite sires. The causative genes and mutations can nowadays be rapidly identified by means of genome-wide association studies combined with next generation DNA sequencing, prov...

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Détails bibliographiques
Publié dans:BMC Genomics
Auteurs principaux: Sartelet, Arnaud, Li, Wanbo, Pailhoux, Eric, Richard, Christophe, Tamma, Nico, Karim, Latifa, Fasquelle, Corinne, Druet, Tom, Coppieters, Wouter, Georges, Michel, Charlier, Carole
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2015
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404575/
https://ncbi.nlm.nih.gov/pubmed/25895751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12864-015-1528-y
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