Cytosolic Phospholipase A2 Modulates TLR2 Signaling in Synoviocytes

Rheumatoid arthritis (RA) is an autoimmune disease characterized by chronic synovitis leading to destruction of cartilage and bone. PLA2 enzymes are key players in inflammation regulating the release of unsaturated fatty acids such as arachidonic acid (AA), a precursor of pro-inflammatory eicosanoid...

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Publicat a:PLoS One
Autors principals: Sommerfelt, Randi M., Feuerherm, Astrid J., Skuland, Trine, Johansen, Berit
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404349/
https://ncbi.nlm.nih.gov/pubmed/25893499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0119088
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