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Janus Particles as Artificial Antigen-Presenting Cells for T Cell Activation
Here we show that the multifunctionality of Janus particles can be exploited for in vitro T cell activation. We engineer bifunctional Janus particles on which the spatial distribution of two ligands, anti-CD3 and fibronectin, mimics the “bull’s eye” protein pattern formed in the membrane junction be...
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| Veröffentlicht in: | ACS Appl Mater Interfaces |
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| Hauptverfasser: | , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2014
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4404154/ https://ncbi.nlm.nih.gov/pubmed/25343426 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/am505510m |
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