Antagonism of miR-328 Increases the Antimicrobial Function of Macrophages and Neutrophils and Rapid Clearance of Non-typeable Haemophilus Influenzae (NTHi) from Infected Lung

Pathogenic bacterial infections of the lung are life threatening and underpin chronic lung diseases. Current treatments are often ineffective potentially due to increasing antibiotic resistance and impairment of innate immunity by disease processes and steroid therapy. Manipulation miRNA directly re...

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Veröffentlicht in:PLoS Pathog
Hauptverfasser: Tay, Hock L., Kaiko, Gerard E., Plank, Maximilian, Li, JingJing, Maltby, Steven, Essilfie, Ama-Tawiah, Jarnicki, Andrew, Yang, Ming, Mattes, Joerg, Hansbro, Philip M., Foster, Paul S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2015
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Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4404141/
https://ncbi.nlm.nih.gov/pubmed/25894560
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1004549
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