Oridonin stabilizes retinoic acid receptor alpha through ROS-activated NF-κB signaling

BACKGROUND: Retinoic acid receptor alpha (RARα) plays an essential role in the regulation of many biological processes, such as hematopoietic cell differentiation, while abnormal RARα function contributes to the pathogenesis of certain diseases including cancers, especially acute promyelocytic leuke...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Cao, Yang, Wei, Wei, Zhang, Nan, Yu, Qing, Xu, Wen-Bin, Yu, Wen-Jun, Chen, Guo-Qiang, Wu, Ying-Li, Yan, Hua
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403721/
https://ncbi.nlm.nih.gov/pubmed/25886043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1219-8
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