Requirement for Chloride Channel Function during the Hepatitis C Virus Life Cycle

Hepatocytes express an array of plasma membrane and intracellular ion channels, yet their role during the hepatitis C virus (HCV) life cycle remains largely undefined. Here, we show that HCV increases intracellular hepatic chloride (Cl(−)) influx that can be inhibited by selective Cl(−) channel bloc...

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Bibliografiske detaljer
Udgivet i:J Virol
Main Authors: Igloi, Zsofia, Mohl, Bjorn-Patrick, Lippiat, Jonathan D., Harris, Mark, Mankouri, Jamel
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Virus-Cell Interactions
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403416/
https://ncbi.nlm.nih.gov/pubmed/25609806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02946-14
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