A role for Kalirin-7 in nociceptive sensitization via activity-dependent modulation of spinal synapses

Synaptic plasticity is the cornerstone of processes underlying persistent nociceptive activity-induced changes in normal nociceptive sensitivity. Kalirin-7 is a multifunctional guanine-nucleotide-exchange factor (GEF) for Rho GTPases that is characterized by its localization at excitatory synapses,...

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Bibliographic Details
Published in:Nat Commun
Main Authors: Lu, Jianning, Luo, Ceng, Bali, Kiran Kumar, Xie, Rou-Gang, Mains, Richard E., Eipper, Betty A., Kuner, Rohini
Format: Artigo
Language:Inglês
Published: Nature Pub. Group 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403379/
https://ncbi.nlm.nih.gov/pubmed/25865668
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7820
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