Whole-exome SNP array identifies 15 new susceptibility loci for psoriasis

Genome-wide association studies (GWASs) have reproducibly associated ∼40 susceptibility loci with psoriasis. However, the missing heritability is evident and the contributions of coding variants have not yet been systematically evaluated. Here, we present a large-scale whole-exome array analysis for...

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Vydáno v:Nat Commun
Hlavní autoři: Zuo, Xianbo, Sun, Liangdan, Yin, Xianyong, Gao, Jinping, Sheng, Yujun, Xu, Jinhua, Zhang, Jianzhong, He, Chundi, Qiu, Ying, Wen, Guangdong, Tian, Hongqing, Zheng, Xiaodong, Liu, Shengxiu, Wang, Wenjun, Li, Weiran, Cheng, Yuyan, Liu, Longdan, Chang, Yan, Wang, Zaixing, Li, Zenggang, Li, Longnian, Wu, Jianping, Fang, Ling, Shen, Changbing, Zhou, Fusheng, Liang, Bo, Chen, Gang, Li, Hui, Cui, Yong, Xu, Aie, Yang, Xueqin, Hao, Fei, Xu, Limin, Fan, Xing, Li, Yuzhen, Wu, Rina, Wang, Xiuli, Liu, Xiaoming, Zheng, Min, Song, Shunpeng, Ji, Bihua, Fang, Hong, Yu, Jianbin, Sun, Yongxin, Hui, Yan, Zhang, Furen, Yang, Rongya, Yang, Sen, Zhang, Xuejun
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2015
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403312/
https://ncbi.nlm.nih.gov/pubmed/25854761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms7793
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