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Characterization of global loss of imprinting in fetal overgrowth syndrome induced by assisted reproduction

Embryos generated with the use of assisted reproductive technologies (ART) can develop overgrowth syndromes. In ruminants, the condition is referred to as large offspring syndrome (LOS) and exhibits variable phenotypic abnormalities including overgrowth, enlarged tongue, and abdominal wall defects....

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Publicat a:Proc Natl Acad Sci U S A
Autors principals: Chen, Zhiyuan, Hagen, Darren E., Elsik, Christine G., Ji, Tieming, Morris, Collin James, Moon, Laura Emily, Rivera, Rocío Melissa
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2015
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403167/
https://ncbi.nlm.nih.gov/pubmed/25825726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1422088112
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