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Unraveling the association between mRNA expressions and mutant phenotypes in a genome-wide assessment of mice

High-throughput gene expression profiling has revealed substantial leaky and extraneous transcription of eukaryotic genes, challenging the perceptions that transcription is strictly regulated and that changes in transcription have phenotypic consequences. To assess the functional implications of mRN...

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Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Liao, Ben-Yang, Weng, Meng-Pin
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403156/
https://ncbi.nlm.nih.gov/pubmed/25825715
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1415046112
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