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Angiotensin-(1-7) attenuates airway remodelling and hyperresponsiveness in a model of chronic allergic lung inflammation

BACKGROUND AND PURPOSE: A long-term imbalance between pro- and anti-inflammatory mediators leads to airway remodelling, which is strongly correlated to most of the symptoms, severity and progression of chronic lung inflammation. The Angiotensin-(1-7) [Ang-(1-7)]/Mas receptor axis of the renin-angiot...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Magalhães, G S, Rodrigues-Machado, M G, Motta-Santos, D, Silva, A R, Caliari, M V, Prata, L O, Abreu, S C, Rocco, P R M, Barcelos, L S, Santos, R A S, Campagnole-Santos, M J
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403097/
https://ncbi.nlm.nih.gov/pubmed/25559763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.13057
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