A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury

Group B streptococci (GBS) are Gram-positive bacteria that cause infections in utero and in newborns. We recently showed that the GBS pigment is hemolytic and increased pigment production promotes bacterial penetration of human placenta. However, mechanisms utilized by the hemolytic pigment to induc...

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Detalhes bibliográficos
Publicado no:EMBO Mol Med
Main Authors: Whidbey, Christopher, Vornhagen, Jay, Gendrin, Claire, Boldenow, Erica, Samson, Jenny Mae, Doering, Kenji, Ngo, Lisa, Ezekwe, Ejiofor A D, Gundlach, Jens H, Elovitz, Michal A, Liggitt, Denny, Duncan, Joseph A, Adams Waldorf, Kristina M, Rajagopal, Lakshmi
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Research Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403049/
https://ncbi.nlm.nih.gov/pubmed/25750210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404883
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