A streptococcal lipid toxin induces membrane permeabilization and pyroptosis leading to fetal injury

Group B streptococci (GBS) are Gram-positive bacteria that cause infections in utero and in newborns. We recently showed that the GBS pigment is hemolytic and increased pigment production promotes bacterial penetration of human placenta. However, mechanisms utilized by the hemolytic pigment to induc...

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Publicado en:EMBO Mol Med
Autores principales: Whidbey, Christopher, Vornhagen, Jay, Gendrin, Claire, Boldenow, Erica, Samson, Jenny Mae, Doering, Kenji, Ngo, Lisa, Ezekwe, Ejiofor A D, Gundlach, Jens H, Elovitz, Michal A, Liggitt, Denny, Duncan, Joseph A, Adams Waldorf, Kristina M, Rajagopal, Lakshmi
Formato: Artigo
Lenguaje:Inglês
Publicado: BlackWell Publishing Ltd 2015
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Research Articles
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403049/
https://ncbi.nlm.nih.gov/pubmed/25750210
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/emmm.201404883
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