Trade-Offs in the Effects of the Apolipoprotein E Polymorphism on Risks of Diseases of the Heart, Cancer, and Neurodegenerative Disorders: Insights on Mechanisms from the Long Life Family Study

The lack of evolutionary established mechanisms linking genes to age-related traits makes the problem of genetic susceptibility to health span inherently complex. One complicating factor is genetic trade-off. Here we focused on long-living participants of the Long Life Family Study (LLFS), their off...

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Detalhes bibliográficos
Publicado no:Rejuvenation Res
Main Authors: Kulminski, Alexander M., Arbeev, Konstantin G., Culminskaya, Irina, Ukraintseva, Svetlana V., Stallard, Eric, Province, Michael A., Yashin, Anatoli I.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc. 2015
Assuntos:
Original Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403014/
https://ncbi.nlm.nih.gov/pubmed/25482294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/rej.2014.1616
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