Determination of Anti-Adeno-Associated Virus Vector Neutralizing Antibody Titer with an In Vitro Reporter System

Adeno-associated virus (AAV) vectors are a platform of choice for in vivo gene transfer applications. However, neutralizing antibodies (NAb) to AAV can be found in humans and some animal species as a result of exposure to the wild-type virus, and high-titer NAb develop following AAV vector administr...

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Publicat a:Hum Gene Ther Methods
Autors principals: Meliani, Amine, Leborgne, Christian, Triffault, Sabrina, Jeanson-Leh, Laurence, Veron, Philippe, Mingozzi, Federico
Format: Artigo
Idioma:Inglês
Publicat: Mary Ann Liebert, Inc. 2015
Matèries:
Protocol
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4403012/
https://ncbi.nlm.nih.gov/pubmed/25819687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/hgtb.2015.037
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