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Actinomycin D inhibits cell proliferations and promotes apoptosis in osteosarcoma cells

Actinomycin D (ActD), a well known transcription inhibitors, has been widely reported to induce cell apoptosis in several types of tumor cells by inhibiting the anti-apoptotic gene transcriptions. However, how ActD affects osteosarcoma cells survival and its molecular mechanism is currently unclear....

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Detalhes bibliográficos
Publicado no:Int J Clin Exp Med
Main Authors: Lu, Dai-Feng, Wang, Yan-Song, Li, Chao, Wei, Guo-Jun, Chen, Rui, Dong, Da-Ming, Yao, Meng
Formato: Artigo
Idioma:Inglês
Publicado em: e-Century Publishing Corporation 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402766/
https://ncbi.nlm.nih.gov/pubmed/25932119
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