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RNA chaperones buffer deleterious mutations in E. coli

Both proteins and RNAs can misfold into non-functional conformations. Protein chaperones promote native folding of nascent polypeptides and refolding of misfolded species, thereby buffering mutations that compromise protein structure and function. Here, we show that RNA chaperones can also act as mu...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Rudan, Marina, Schneider, Dominique, Warnecke, Tobias, Krisko, Anita
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402597/
https://ncbi.nlm.nih.gov/pubmed/25806682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.04745
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