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A comparative study of disease genes and drug targets in the human protein interactome

BACKGROUND: Disease genes cause or contribute genetically to the development of the most complex diseases. Drugs are the major approaches to treat the complex disease through interacting with their targets. Thus, drug targets are critical for treatment efficacy. However, the interrelationship betwee...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Sun, Jingchun, Zhu, Kevin, Zheng, W Jim, Xu, Hua
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2015
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402590/
https://ncbi.nlm.nih.gov/pubmed/25861037
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2105-16-S5-S1
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