CYP7A1 Gene Polymorphism Located in the 5′ Upstream Region Modifies the Risk of Coronary Artery Disease

Background. 7-Alpha cholesterol hydroxylase (CYP7A1), the first enzyme of classic conversion pathway leading from cholesterol to bile acids synthesis, is encoded by CYP7A1 gene. Its single nucleotide polymorphisms (SNPs) influence serum lipid levels and may be related to impaired lipid profile leadi...

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Bibliografiske detaljer
Udgivet i:Dis Markers
Main Authors: Iwanicki, Tomasz, Balcerzyk, Anna, Niemiec, Pawel, Nowak, Tomasz, Ochalska-Tyka, Anna, Krauze, Jolanta, Kosiorz-Gorczynska, Sylwia, Grzeszczak, Wladyslaw, Zak, Iwona
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2015
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402502/
https://ncbi.nlm.nih.gov/pubmed/25944972
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/185969
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