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Characterization of a Novel Antisense RNA in the Major Pilin Locus of Neisseria meningitidis Influencing Antigenic Variation

Expression of type four pili (Tfp) is essential for virulence in Neisseria meningitidis. Pili mediate adhesion, bacterial aggregation, and DNA uptake. In N. meningitidis, the major pilin subunit is encoded by the pilE gene. In some strains, PilE is subject to phase and antigenic variation, which can...

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Bibliografiske detaljer
Udgivet i:J Bacteriol
Main Authors: Tan, Felicia Y. Y., Wörmann, Mirka E., Loh, Edmund, Tang, Christoph M., Exley, Rachel M.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2015
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402397/
https://ncbi.nlm.nih.gov/pubmed/25755192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00082-15
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