Linking the aryl hydrocarbon receptor with altered DNA methylation patterns and developmentally induced aberrant antiviral CD8(+) T cell responses

Successfully fighting infection requires a properly tuned immune system. Recent epidemiological studies link exposure to pollutants that bind the aryl hydrocarbon receptor (AHR) during development with poorer immune responses later in life. Yet, how developmental triggering of AHR durably alters imm...

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Vydáno v:J Immunol
Hlavní autoři: Winans, Bethany, Nagari, Anusha, Chae, Minho, Post, Christina M., Ko, Chia-I, Puga, Alvaro, Kraus, W. Lee, Lawrence, B. Paige
Médium: Artigo
Jazyk:Inglês
Vydáno: 2015
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402273/
https://ncbi.nlm.nih.gov/pubmed/25810390
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1402044
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