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Modeling Maintenance of Long-Term Potentiation in Clustered Synapses: Long-Term Memory without Bistability

Memories are stored, at least partly, as patterns of strong synapses. Given molecular turnover, how can synapses maintain strong for the years that memories can persist? Some models postulate that biochemical bistability maintains strong synapses. However, bistability should give a bimodal distribut...

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Bibliografische gegevens
Gepubliceerd in:Neural Plast
Hoofdauteur: Smolen, Paul
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Hindawi Publishing Corporation 2015
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402204/
https://ncbi.nlm.nih.gov/pubmed/25945261
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/185410
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