Llwytho...

Genetic Heterogeneity of Pseudoxanthoma Elasticum: The Chinese Signature Profile of ABCC6 and ENPP1 Mutations

Pseudoxanthoma elasticum (PXE), an autosomal recessive disorder characterized by ectopic mineralization, is caused by mutations in the ABCC6 gene. We examined clinically 29 Chinese PXE patients from unrelated families, so far the largest cohort of Asian PXE patients. In a subset of 22 patients, we s...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Invest Dermatol
Prif Awduron: Jin, Liang, Jiang, Qiujie, Wu, Zhengsheng, Shao, Changxia, Zhou, Yong, Yang, Luting, Uitto, Jouni, Wang, Gang
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2015
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402129/
https://ncbi.nlm.nih.gov/pubmed/25615550
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.10
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