Phosphorylated S6 Kinase and S6 Ribosomal Protein are Diagnostic Markers of Antibody Mediated Rejection in Heart Allografts

BACKGROUND: Anti-MHC class I alloantibodies have been implicated in the processes of acute and chronic rejection. These antibodies (Ab) bind to endothelial cells (EC) and transduce signals leading to the activation of cell survival and proliferation pathways, including Src, FAK, mTOR, and downstream...

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Detalhes bibliográficos
Publicado no:J Heart Lung Transplant
Main Authors: Li, Fang, Wei, Jennifer, Valenzuela, Nicole M., Lai, Chi, Zhang, Qiuheng, Gjertson, David, Fishbein, Michael C, Kobashigawa, Jon A, Deng, Mario, Reed, Elaine F.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4402106/
https://ncbi.nlm.nih.gov/pubmed/25511749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.healun.2014.09.047
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