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Rapamycin and aging: When, for how long, and how much?

The drug rapamycin is the only pharmacological agent thus far shown to reproducibly extend lifespan and delay a subset of age-associated pathologies in multiple strains of mice. Unfortunately, the vast majority of aging-related studies on rapamycin in mice have been performed at a single dose of the...

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Detalhes bibliográficos
Publicado no:J Genet Genomics
Autor principal: Kaeberlein, Matt
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401992/
https://ncbi.nlm.nih.gov/pubmed/25269671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgg.2014.06.009
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