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Promotion of Cell Migration by Neural Cell Adhesion Molecule (NCAM) Is Enhanced by PSA in a Polysialyltransferase-Specific Manner

Neural cell adhesion molecule 140 (NCAM-140) is a glycoprotein and always highly polysialylated in cancer. Functions of polysialic acid (PSA) that binds to N-glycan termini on NCAM remain unclear. ldlD-14 cells, a CHO cell mutant deficient in UDP-Gal 4-epimerase, are useful for structural and functi...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Guan, Feng, Wang, Xin, He, Fa
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2015
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401701/
https://ncbi.nlm.nih.gov/pubmed/25885924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0124237
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