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Hyperthermia Sensitizes Glioma Stem-like Cells to Radiation By Inhibiting AKT Signaling

Glioma stem-like cells (GSCs) are a subpopulation of cells in tumors that are believed to mediate self-renewal and relapse in glioblastoma (GBM), the most deadly form of primary brain cancer. In radiation oncology, hyperthermia is known to radiosensitize cells and it is re-emerging as a treatment op...

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Bibliographische Detailangaben
Veröffentlicht in:Cancer Res
Hauptverfasser: Man, Jianghong, Shoemake, Jocelyn D., Ma, Tuopu, Rizzo, Anthony E., Godley, Andrew R., Wu, Qiulian, Mohammadi, Alireza M., Bao, Shideng, Rich, Jeremy N., Yu, Jennifer S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2015
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4401644/
https://ncbi.nlm.nih.gov/pubmed/25712125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-14-3621
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